Hacettepe University has achieved a significant international success aimed at developing personalised medicine strategies. The ‘BioPATH-SAID’ project, prepared under the leadership of Prof. Dr. Seza Özen, a faculty member of the Department of Paediatric Rheumatology at our University's Faculty of Medicine, has been officially awarded funding under the European Union's prestigious EP PerMed JTC 2025 call for proposals, which focuses on pharmacogenomics.
In this highly competitive process, where only 22 projects were selected from among the preliminary proposals submitted across Europe, Hacettepe University's role as the main coordinator of the project has reinforced our university's leadership in the global scientific arena.
This comprehensive research project, to be conducted within our University's Faculty of Medicine, brings together faculty members from the Department of Paediatric Rheumatology and the Department of Medical Genetics in a multidisciplinary structure. The project team includes Prof. Dr. Seza Özen, Prof. Dr. Yelda Bilginer, Prof. Dr. Zihni Ekim Taşkıran, Assoc. Prof. Dr. Erdal Sağ, Assoc. Prof. Dr. Beren Karaosmanoğlu, and Dr. Gözde İmren as researchers.
The work will be based at our university's Translational Medicine Laboratory. Led by Turkey, the project will involve collaboration with academic partners from Belgium, Germany and Denmark to manage an international data and analysis network.
The project, known as BioPATH-SAID, stands for "Pathway-Driven Biomarker Discovery for Guiding Precision Therapy in Undefined Systemic Autoinflammatory Diseases" project aims to elucidate the underlying immunological mechanisms at the molecular level in paediatric patients diagnosed with undiagnosed systemic autoinflammatory disease (uSAID).
Within the scope of the research, data obtained through genomic, transcriptomic and proteomic methods will be integrated and analysed. This holistic approach aims to predict pathway-targeted treatment options by creating personalised diagnostic subgroups.
The study aims to unravel the pathogenesis of undiagnosed SAID patients and transform the diagnosis and treatment processes of autoinflammatory diseases in children on a scientific basis.
Detailed information can be accessed via the link below.
https://www.eppermed.eu/funding-projects/projects-results/project-database/biopath-said/
